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USMLE-STEP-1 Exam Questions & Answers

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USMLE-STEP-1 Exam Questions & Answers

Vendor: USMLE

Certifications: USMLE Certifications

Exam Code: USMLE-STEP-1

Exam Name: United States Medical Licensing Step 1

Updated: May 31, 2026

Q&As: 847 ( View Details)

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USMLE-STEP-1 Online Practice Questions and Answers

Questions 1

Your patient reports that several days earlier he "threw his back out" when he bent from the waist and picked up a very heavy package. The pain was immediate and extended from his hip, down the back of the thigh, and into his leg and foot. As he lies on the examining table, you raise his leg by the foot keeping the knee extended and elicit intense pain over the distribution of the sciatic nerve. An MRI scan confirms your conclusion that your patient has a herniated intervertebral disk between the fourth and fifth lumbar vertebrae. Intervertebral disks may protrude or rupture in any direction, but they most commonly protrude in which direction?

A. anteriorly

B. anterolaterally

C. laterally

D. posteriorly

E. posterolaterally

Show Answer
Questions 2

A 75-year-old male presented with a 6-month history of early satiety and with upper abdominal discomfort for many years. Physical examination revealed mild epigastric tenderness. Esophago-gastroduodenoscopy showed a large, ulcerated mass in the upper stomach, which was found to be cancerous. Surgery resulting in the removal of the gastric fundus was performed. After successful surgery, the patient was advised to eat small portions and to drink small volumes because of which of the following?

A. almost complete absence of gastric motility

B. distorted emptying of liquids

C. inadequate mixing of large food boluses

D. lack of receptive relaxation in the stomach

E. weaker and slower propulsion of food toward the pylorus

Show Answer
Questions 3

A 35-year-old male with end-stage renal disease must undergo a kidney transplant. Which of the following is true of immunologic suppression for transplantation?

A. It can occur by antilymphocyte globulin.

B. It cannot be achieved by cyclosporine administration.

C. It cannot occur by lymphoid irradiation.

D. It is facilitated by gamma interferon administration.

E. It is not likely to respond to steroid administration.

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