USMLE Online Practice Questions and Answers

A 25-year-old man is brought to the emergency department because of a 6-day history of fever, severe muscle pain, and diffuse, painful swelling of his neck, underarms, and groin area. The symptoms began after returning from a camping trip in New Mexico. He appears ill and lethargic and can barely answer questions. His temperature is 39.2°C (102.5°F), pulse is 120/min, respirations are 22/min, and blood pressure is 110/70 mmHg. Physical examination shows generalized scattered black maculae. Examination of the right upper extremity shows an erythematous, solid, tender mass on the underside of the upper extremity just above the elbow; the mass is draining blood and necrotic material. The most effective antibiotic for this patient's disorder will interfere with which of the following cellular processes or enzymes?

A. Cell wall synthesis

B. DNA helicase

C. Glucuronosyltransferase

D. Proteasomal assembly

E. Tetrahydrofolate reductase

A 45-year-old male is brought to the emergency department by the police who found him wandering around a park at midnight. Physical examination reveals bilateral hand tremors. Laboratory tests reveal elevated serum gamma-glutamyl transferase. Thirty hours after he is admitted to the hospital he develops generalized seizures. The most appropriate treatment for this patient's seizures is

A. carbamazepine

B. lorazepam

C. phenytoin

D. thiopental

E. zolpidem

Which of the following is not directly related to a drug toxicity of Nitroglycerin?

A. Headaches

B. Tachycardia

C. Dizziness

D. Projectile vomiting

Which of the following terms correspond with the phrase: a woman that is pregnant?

A. Gravida

B. Parity

C. Spermatogonia

D. Zonapellucida

Which of the following is not an associated change during the antepartum period?

A. Increased urination frequency

B. Increased respiratory requirements

C. Decreased basal metabolic rate

D. Goodell's sign

Which of the following syndromes corresponds to: chromosomal deficit of #18?

A. Dubin-Johnson syndrome

B. Fanconi's syndrome

C. Edward's syndrome

D. Cri-du-chat syndrome

A 75-year-old man presents to his physician with complaints of nocturia, urinary urgency, and a feeling that he could not completely empty his bladder. A digital rectal exam reveals a firm, enlarged prostate. A bone scan is ordered and shows positivity in multiple vertebral bodies. Elevation of which of the following substances would be most strongly associated with the development of bone lesions?

A. Prostatic acid phosphatase

B. Prostate-specific antigen

C. Serum alkaline phosphatase

D. Tartrate-resistant acid phosphatase

E. Urinary hydroxyproline

Angiotensin can directly cause the release of ____ from the adrenal cortex.

A. Renin

B. Aldosterone

C. Calcitonin

D. Thyroxine

Which of the following arteries is the most frequent site of coronary artery stenosis?

A. LCA

B. RCA

C. LAD

D. PD

Which of the following types of cytokines is responsible for the growth and maturation of B cells?

A. Interleukin-1

B. Interleukin-2

C. Interleukin-4

D. Interleukin-7